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CYP3A4 zu Noroxymorphon umgewandelt.35 Die primären Oxycodon-Metaboliten weisen ebenfalls eine Affinität für μ-Opioidrezeptoren auf. Noroxycodon besitzt jedoch nur 17 % der Potenz der Ausgangssubstanz, während Oxymorphon trotz seiner hohen Affinität zu μ-Opioidrezeptoren nur in...
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